The GenapSys Sequencer
Transforming Genomics Applications

Go in-depth on these key applications for the GenapSys Sequencer.

Targeted Resequencing

Targeted resequencing is a variation of re-sequencing where only a small subset of the genome is sequenced, such as the exome, a particular chromosome, a set of genes or a region of interest. By focusing all of the sequencing on a small region of the genome,
it is possible to detect low levels of variation that might have otherwise been missed. It is an important tool for Oncology research and variant calling.

Targeted sequencing on the GenapSys Sequencer focuses on regions of interest and avoids uninformative portions, to maximize sequencing utility and samples per run.

  • Robust sequencing of a set of genes or regions of interest
  • Low price per run and low price per sample
  • Wide range of throughputs suitable for various applications, with different chips. e.g. 16 million sensor chip, more than 1.2-2.0 Gb of highly accurate DNA sequence per run average read-length of >150 bps
  • Compatible with amplicon-based or hybridization capture-based libraries, and PCR products

Variant Calling on the GenapSys Sequencing Platform


Oncology Research Applications using the GenapSys Sequencing Platform



Small Genome Sequencing

Small genome sequencing (≤10 Mb) involves sequencing the entire genome of a bacterium, virus, archaea, or other microorganism, and then comparing the sequence to a known reference. Sequencing small microbial genomes can be useful for food testing, public health, infectious disease surveillance, molecular epidemiology studies, and environmental metagenomics.

The GenapSys Sequencing Platform, using the 16M chip, generates 1.2 – 2.0 Gb of highly accurate sequencing output per run, and is the ideal tool for addressing these applications.

  • Robust sequencing of entire small genomes
  • Low price per run and low price per sample
  • More than 1.2 Gb of highly accurate DNA sequence per run
  • Highly uniform genome coverage for viruses, bacteria, and other microbes


Small Genome Sequencing on the GenapSys Sequencer


See the paper that demonstrates our sequencer’s >80% of bases >Q30.

Our technology was validated against leading NGS systems, with the sequencing of several different microbial genomes, targeted sequencing of the human genome, and sequencing of a targeted panel of cancer-associated genes.


View webinar by David Harrison of Jackson Laboratory

Originally presented at ASHG 2019, this webinar shares the findings by Jackson Laboratory on their evaluation of GenapSys sequencing system on reproducibility, throughput, and accuracy.






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